The marine park encompasses over 125.70 km2 (48.53 sq mi) and comprises the boundaries of both the Peninsula of Karaburun and the Island of Sazan.

It is home to a vast array of landforms, including mountains, caves, islands, depressions, bays, cliffs, canyons and rocky coasts, all contributing to an exceptionally considerable biological diversity.

The island's climate is not mediterranean but rather subtropical on account of its warm winters and hot summers, resembling those of the south of Crete, of Tunisia and Egypt.

[7][8] The marine park features ruins of sunken ancient Greek, Roman and World War II ships, rich underwater fauna, steep cliffs and giant caves, ancient inscriptions of sailors on shore, secluded beaches and scenic views of the Adriatic and Ionian Sea.

It lies primarily between latitudes 40° and 26° N and longitudes 19° and 18° E. The marine park comprises 125.70 km2 (48.53 sq mi) in Vlorë County in southwestern Albania.

In terms of geology, the peninsula belongs to the Ceraunian Mountains, which rises steeply along the Albanian Ionian Sea Coast.

[9] The marine park's mountainous terrain and its geographic features result in the area being of high interest to both visitors and researchers.

The peninsula was shaped into its current form over several geological eras with the tectonic merging of Paleozoic schist formations, Mesozoic limestone and marble deposits.

The diverse landscapes of the park, with an exceptionally considerable marine and terrestrial life free of any marks of human disturbance, maintain a particular appeal.

Sea turtles, seals, and dolphins are considered to reside in the park area, although sufficient regularity of occurrences is unclear.

[15] Outstanding is the mediterranean monk seal, one of the most endangered mammals in the world, mostly seek refuge in the inaccessible caves and canyons of the park.

The coasts along Karaburun and Sazan are rocky with significant calcareous limestone cliffs, properly covered with Mediterranean maquis with a dominance of lentisk, kermes oak and Phoenicean juniper.

The western coasts of are incised by caves and canyons and characterized by high vertical cliffs that appear underwater at great depths.