Small Prespa Lake in particular has been recognized as an important wetland ecosystems favoring breeding and feeding of rare water bird species.

In Greece the villages surrounding the lake are Agios Germanos, Laimos, Milionas, Platy, Kallithea, Lefkonas, Prespes, Karyes, Mikrolimni, Oxia, Pyli and Vrontero.

During 1970, significant amounts of water from the Devoll river was diverted into the lake with the intention to use it latter during the summer time for the irrigation purposes.

Due to the high suspended solids in the river water significant siltation did occur on the Albanian side.

[3] Small Prespa Lake contains the island of Agios Achilleios (Saint Achilleus); in February 1948, in the midst of the Greek Civil War, Nikos Zachariadis, the General Secretary of the Communist Party of Greece, married Roula Koukoulou, his long-time lover, on this island, in a widely publicized ceremony.