The Karachi Port Trust (KPT) (Urdu: ادارہِ تولیتِ بندرگاہ کراچی) is a Pakistani federal government agency, under the administrative control of the Federal Maritime Secretary that oversees the operations of the Port of Karachi, one of South Asia's largest and busiest deep-water seaports which handles over 90% of the nation's foreign trade.

The agency is headquartered at the colonial-era Karachi Port Trust Building.

The Karachi Port Trust was then established by the Act IV of 1886, effective from 1 April 1887.

The chairman, who is appointed by the Federal Government, is also the chief executive.

KPT has undertaken programs to protect and expand mangroves around the Port of Karachi.