In 1772, the house was bought for 4,000 forints by Dimitrije Karamata, an immigrant from Katranitsa in Aegean Macedonia which at that time belonged to Turkey (nowadays Pyrgoi, Greece).

Jovan Karamat, son of Dimitrije, built a new story to the middle part of the house and finished the overall adaptation of the building in 1827.

At the time of the Austro-Ottoman war, in 1788, Emperor Joseph II stayed in the Karamata family house, along with his headquarter members.

For that occasion, a big Austrian two-headed eagle, carved in wood and colored, probably the work of a local carver, was placed on the ceiling of the first floor, along with the symbols of the Monarchy.

The house was also the venue of the meetings of the Main National Board of the Voivodeship of Serbia and Banat of Temeschwar, where Atanas Karamata at the time was its treasurer.