The album featured a story written by Irish playwright Marina Carr narrated by Casey, produced by Niall Vallely and Leib Ostrow, and featured contributions from Martin Hayes & Dennis Cahill, Iarla Ó Lionaird, Máiréad Ní Mhaonaigh, Michael McGoldrick, Mel Mercier and Robbie Overson.

In 2005, Casey released Chasing the Sun featuring Irish traditional and folk songs which she learned from her mother and maternal grandmother.

It features a duet with Irish chart-topper Mick Flannery as well as contributions from Abigail Washburn and Aoife O’Donovan, and was produced by Niall Vallely.

A departure from the traditional music she has focused on for many years, Two More Hours draws on Casey's lifelong love of R&B, jazz and blues in creating a vibrant new mix of sounds.

Vallely's string arrangements help meld together a cast of Ireland's musicians from the worlds of classical, folk and rock music including Ken Rice, Kate Ellis, Sean Og Graham (of Beoga), Trevor Hutchinson, Eoghan Regan, Danny Byrt and Caoimhín Vallely.

In 2018 Karan helped to found FairPlé which is an organization aimed at achieving fairness and gender balance for female performers in Irish traditional and folk musics.

Drawing inspiration from contemporary folk writers Janis Ian, Eliza Gilkyson, Mick Flannery and Bob Dylan, the album displays Casey's impressive talent as a songwriter.

She is joined on vocals by some of the women singers she's long-admired, including Karen Matheson, Niamh Dunne, Pauline Scanlon, Maura O'Connell and Aoife O Donovan.

[6] Casey has also collaborated with Bela Fleck, Maura O'Connell, Tim O'Brien, Lunasa, The Boston Pops Orchestra, The Dubliners & Imelda May, A Stór Mo Chroí (featuring John Spillane, Lumiere and Muireann Nic Amhlaoibh), among others.