Kareli (Georgian: ქარელი) is a town in Shida Kartli, Georgia, located on the right bank of the Mtkvari, 94 km west of the country's capital of Tbilisi.

Kareli became the district center in 1939, transformed into a township in 1962, declared a city in 1981.

There is a railway station, industrial enterprises, healthcare, educational and cultural institutions in Kareli.

[2] Kareli has a humid subtropical climate with moderately cold winters and long warm summers.

The town's environs are a home to several architectural monuments of medieval Georgia such as the churches of Zghuderi, Samtsevrisi, Ruisi, and Kintsvisi, and the fortress of Ortubani (Dzama).