In her first 13 seasons as a head coach, Aston's teams have averaged 22 wins per year and have made a combined ten postseason appearances.

Prior to becoming Baylor's associate head coach, she served eight seasons in the same capacity at The University of Texas at Austin under Jody Conradt.

After a run to the final four of the WNIT in 2011, Aston resigned on April 6, 2011 and soon thereafter accepted the head coaching position at North Texas in order to be closer to her family in Arkansas.

[5] On April 11, 2011, Karen Aston was named the sixth head coach of the University of North Texas (UNT) women's basketball program.

[7] Aston was named the fourth head coach in University of Texas women's basketball history on April 3, 2012.

In her final seven seasons combined at Texas, Aston's teams averaged 24.6 wins per year, making six NCAA tournament appearances.

[10] Six of Aston's Texas players (Nneka Enemkpali, Imani McGee-Stafford, Ariel Atkins, Joyner Holmes, Sug Sutton and Charli Collier) were drafted by WNBA teams.

Four of the top-eight single-season team rebounding averages in Texas history came during Aston's tenure, as did five of the top-nine best seasons in field-goal percentage defense.