Karen Casey (7 January 1956 – 15 October 2021)[2] was an Australian interdisciplinary artist of the Palawa people, Australia.

[3] Casey attended art school at the Tasmanian College of Advanced Education where she studied silversmithing.

[2] Casey began exhibiting her artwork in the late 1980s, and worked for over three decades in a diverse range of media, from painting and printmaking to installation, video, performance and public art.

[5] Her work investigated the "experiential and philosophical understanding of the interrelationships between various cultural and spiritual traditions and aspects of contemporary western science."

Using MRI and CT scans of her own liver, she created an animated film called Transplanted, a piece that was described as "remarkable" by art critic Barnaby Smith.