Karen Mirzoyan (Armenian: Կարեն Միրզոյան) is a diplomat of Armenia and previously of the unrecognized Republic of Artsakh.

[3] In September 2014, Mirzoyan led a diplomatic mission to the Basque Parliament.

The Basque Parliament and the Nagorno-Karabakh's legislature passed reciprocal motions recognizing one another's right to national autonomy.

[4] In September 2017, Karen Mirzoyan was succeeded as Foreign Minister of the Artsakh Republic by Masis Mayilyan.

[6] On November 16, 2020, during the political crisis created by the 2020 Nagorno-Karabakh ceasefire agreement, he resigned from his post.