In 2004, Mohlke began working for University of North Carolina, Chapel Hill in the School of Medicine, studying the genetics of complex traits and diseases.
[2] In 2012, Mohlke was a senior author of a study finding new variants of three genes (TBC1D30, KANK1 and PAM[3]) related to diabetes.
[4] Mohlke said: "The exome array allowed us to test a large number of individuals in this case, more than 8,000 people very efficiently.
We expect that this type of analysis will be useful for finding low-frequency variants associated with many complex traits, including obesity or cancer.
"[5] Her research goals include identifying genetic loci responsible for genetic diseases; identifying important locations within these loci for testing; and understanding the functional mechanisms express these genes as physical characteristics.