[1][2] She is best known for her extensive songwriting collaborations with musicians such as Kylie Minogue, Becky Hill, David Guetta, Lily Allen, Sugababes, Zara Larsson, Tiesto, Alesso, Sonny Fodera, Chase & Status, Rita Ora, Fatboy Slim, Sub Focus, Katy B, and many more.

[3] Karen, along with her sister Shelly Poole, was a founding member of the pop duo Alisha's Attic.

[4] The group gained significant success in the 1990s and early 2000s, particularly in the United Kingdom and Europe.

The duo produced three albums, including the platinum-selling Alisha Rules the World.

[7] Ivor Novello and twice Brit Awards nominated Poole has achieved more than 35 Top 20 UK hit singles as a songwriter.