Karen Leigh Prell (born July 26, 1959)[citation needed] is an American puppeteer and animator.

[citation needed] She also performed some characters in other Jim Henson films and has enjoyed a significant second career as a computer animator for such studios as Pixar and DNA.

Her website includes notes about working with Jim Henson and pictures of her custom puppets.

At Dragon Con 2013, Karen Prell was joined by fellow puppeteer Kathryn Mullen as part of the 30th Anniversary of Fraggle Rock where they performed their respective characters.

Since divorcing in 2004, Prell and Quinn have continued to work together on different projects, usually involving the Muppets.