Kariem Hussein (born 4 January 1989)[4] is a Swiss athlete who specialises in the 400 metres hurdles.

His first major success was the gold medal at the 2014 European Championships in Zürich.

His personal best in the event is 48.45, set at a meeting in Zug in 2015 and again at Weltklasse Zürich in 2017.

His father, a former international volleyball player, is Egyptian and his mother is Swiss.

This decision meant Hussein missed the 2020 Summer Olympics in Tokyo.