Karlsbro protested against France's atomic bomb tests on the islands of the South Pacific in her youth.

[2] She holds a law degree from Stockholm University and has studied at the London School of Economics and Political Science (LSE).

From 2006 to 2010, she worked as the chief of staff for Nyamko Sabuni, then Sweden's Minister for Integration and Gender Equality.

Karlsbro has held a number of political offices in Stockholm and most recently she has served as the group leader in Norrtälje between 2014 and 2018.

[7] In addition to her committee assignments, Karlsbro is a member of the European Parliament Intergroup on LGBT Rights[8] and the Responsible Business Conduct Working Group.