At the French Open, her first Grand Slam tournament, she reached the third round in the singles event, beating 22nd-seeded Alona Bondarenko.

At the US Open, she defeated Chan Yung-jan to reach the second round where she lost to American wildcard Ahsha Rolle.

Knapp began the year at the Brisbane International where she lost in the second round of qualifying to Australian wildcard Bojana Bobusic.

[2] After that, Knapp traveled to Paris to play at the Open GdF Suez where she was defeated in the first round of qualifying to Garbiñe Muguruza.

In Bogotá at the Copa Colsanitas, Knapp made it to the semifinals defeating Eva Birnerová, Lourdes Domínguez Lino, and Lara Arruabarrena Vecino.

Seeded eighth at the Gastein Ladies, Knapp reached the semifinal round where she was defeated by eventual champion Yvonne Meusburger.

[11] Despite qualifying for the Western & Southern Open, Knapp lost in the first round to ninth seed Angelique Kerber.

[13] Ranked 55 at the US Open, Knapp reached the third round after wins over American qualifier Grace Min and 22nd seed Elena Vesnina.

In Austria at the Generali Ladies Linz, Knapp upset eighth seed Daniela Hantuchová in her first-round match.

[21] Playing in the Fed Cup tie versus the US, Knapp won both of her rubbers over Christina McHale and Alison Riske.

[25] In Indian Wells at the BNP Paribas Open, Knapp was defeated in round one by American wildcard Taylor Townsend.

Seeded seventh at the Monterrey Open, Knapp was defeated in the first round by eventual finalist Jovana Jakšić.

She advanced to the semifinals after wins over Shahar Pe'er, Polona Hercog, and seventh seed Caroline Garcia.

[33] As the top seed at the Reinert Open, a $50k tournament in Germany, Knapp was defeated in the first round by qualifier Verónica Cepede Royg.

At the İstanbul Cup, Knapp was defeated in the second round by top seed and eventual champion Caroline Wozniacki.

[37] Seeded third at the Tashkent Open, Knapp reached the final after victories over Çağla Büyükakçay, Aliaksandra Sasnovich, Olga Govortsova, and qualifier Lesia Tsurenko.

She beat top seed and defending champion Bojana Jovanovski in the final to win her first WTA title.

[39] Qualifying for the first edition of the Wuhan Open, Knapp lost in the second round to third seed and eventual champion Petra Kvitová.

[40] In Austria at the Generali Ladies Linz, Knapp advanced to the semifinals after wins over fifth seed Sabine Lisicki, Magdaléna Rybáriková, and Tsvetana Pironkova.

After winning her first-round match, she was defeated in the second round by eighth seed and eventual finalist Timea Bacsinszky.

[43] In the Hobart International, Knapp reached the quarterfinals after beating Ajla Tomljanović and top seed Casey Dellacqua.

[45] Competing in Antwerp, Belgium at the Diamond Games, Knapp was defeated in her first-round match by Annika Beck.

[52] Playing in Rome at the Italian Open, Knapp scored a first-round victory over compatriot Francesca Schiavone.

[54] Seeded sixth at the Nürnberger Versicherungscup, Knapp reached the final defeating Antonia Lottner, Anna-Lena Friedsam, qualifier Yulia Putintseva, and Lara Arruabarrena.

[60] In Toronto at the Canadian Open, Knapp lost in the first round to Roberta Vinci; this was the worst loss of her career.

[67] In Spain at the Madrid Open, Knapp was defeated in the second round by sixth seed and eventual champion Simona Halep.

[71] As the top seed at the Internazionali di Brescia, a $50k tournament, Knapp won the title beating Jesika Malečková in the final.

[75] Playing in Cincinnati at the Western & Southern Open, Knapp was defeated in the final round of qualifying by Kurumi Nara.

In Melbourne at the Australian Open, Knapp retired during her first-round match versus Hsieh Su-wei due to injury.

[79] Only main-draw results in WTA Tour, Grand Slam tournaments, Fed Cup and Olympic Games are included in win–loss records.