Karin Marguerite Smyth (born 8 September 1964) is a British Labour Party politician serving as Member of Parliament (MP) for Bristol South since 2015.

[9] On 27 June 2016, she gave support to a series of shadow cabinet resignations aimed at ousting the Labour Leader, Jeremy Corbyn MP, in an open letter to constituents.

[15] On 28 June 2017, Matthew Niblett was jailed for 14 weeks for threatening to kill Smyth over what he felt was her failure to investigate his case.

[16] Karin Smyth is a Co-Chair of the All-Party Parliamentary Group for Choice at the End of Life.

[18] She was appointed as Minister of State at the Department of Health and Social Care following the election of a Labour Government in July 2024.