Karina Duprez (born Karina Julia Descalzó Guzmán on December 23, 1946, in Mexico City, Mexico) is a Mexican director and former actress.
She is a daughter of actress Magda Guzmán and Julián Duprez.
She has two siblings, Gerardo and Mirtha Duprez, and one half-brother, Carlos Falcón, from her mother's second marriage.
At the age of 5, she participated in the theatrical production of Juegos prohibidos.
She later studied acting at the Andres Soller Academy, then at the National Institute of Fine Arts and the Faculty of Philosophy and Literature at the National Autonomous University of Mexico.