Karl Georg Otto Willibald von Kalckstein (14 December 1812 – 6 June 1894) was a Prussian politician.
Kalckstein was born in Gauten (now in Zelenogradsky District), East Prussia, to Carl von Kalckstein, laird of Knauten, Wogau and Schloditten near Mühlhausen, and Charlotte Auguste von Gizycki.
Around 1830, Kalckstein joined the Prussian Army and became an Officer of the Royal Guards Regiment in Berlin.
Eylau and became a member of the Parliament on 11 October 1848 after the delegate Graf Dohna-Lauck resigned his position.
Eylau (Landrat) and member of the North German Confederation parliament and the Reichstag from 1867 - 1873.