In 1860, Karl Otto was registered at the University of Zürich, studying in the Faculty of Philosophy until receiving an academic report (Zeugnis) on 26 Jan 1865.
K. O Hunziker was a pastor in Unterstrass from 1867–1871, then a teacher at the seminary school of Küsnacht, and a professor and headmaster at the state college of higher education.
[1] Karl Otto married Luise Pupikofer 22 Sep 1868 in Bussnang or Wängi, Canton Thurgau, Switzerland.
From 1886–1907 he taught as a private lecturer (Privatdozent) at the Eidgenössische Polytechnikum (today known as ETH Zurich or the Swiss Federal Institute of Technology).
[3] Children of Karl Otto and Luise were Karl Rudolf (5 February 1870, Zürich – 27 May 1946, Winterthur), Barbara Luise (17 June 1871 – 16 October 1871), Marie Julie (23 Jul 1872 – 30 Jun 1938), and Otto Frederick Hunziker (25 Dec 1873 – 16 Nov 1959).