Karl von Bardeleben (7 March 1849 – 19 December 1919) was a German anatomist born in Giessen.
He was the son of surgeon Heinrich Adolf von Bardeleben (1819–1895).
He received his education at the Universities of Greifswald, Heidelberg, Berlin and Leipzig.
In 1886 Bardeleben was founder of the Anatomischer Anzeiger (Annals of Anatomy), a journal that is considered to be one of the better publications on anatomical morphology.
The journal contains many original treatises on topographic and clinical anatomy, embryology, cell and tissue research, as well as microscopic and "submicroscopic" biology.