His career highlights include touring as the supergroup Tabla Beat Science (with Ustad Zakir Hussain, Bill Laswell, Ustad Sultan Khan et al.), 6 solo studio records from 1999 (several other record appearances), the seminal 2005 album "Breathing Under Water" with Anoushka Shankar, scoring and production for the 2019 Bollywood smash hit "Gully Boy", curating 6 acclaimed songs for the Indian Coke Studio in 2012, amongst many others.

[2][better source needed] In 2000, Bill Laswell founded Tabla Beat Science, inviting Kale, along with Zakir Hussain, Talvin Singh, Trilok Gurtu and Sultan Khan.

[2][better source needed] While a Music Production and Performance student at New York University, Kale began playing in bands and working as a session musician.

[8] This episode met both popular and critical acclaim, especially for Kale's take on "Kajar Bin Kaare", a classic from his Tabla Beat Science times, done as a tribute to Ustad Sultan Khan.

[10][11] The album features guitarist Blackstratblues/Warren Mendonsa, Kale's long time collaborator flautist Pandit Ajay Prasanna, and vocalists Papon, Benny Dayal, and Monali Thakur, amongst a host of other musicians.

[19] The EP features Delhi based neo-classical duo Shadow and Light, and Sarod legend Ustaad Amjad Ali Khan.

[20] In the same year, Kale also put out an ambient electronica EP called "Little Whale" with Ankur Tewari, and Gaurav Raina of the Midival Punditz[21] and an accompanying music video.

[28] Entirely conceived and produced in the pandemic, this album sees Kale favour electronic arrangements and only a few collaborations, namely vocalist Malini Awasthi, guitarists Warren Mendonsa and Bhrigu Sahni, and flautist Pandit Ajay Prasanna.

Kale has composed for crossover and Bollywood films including Chutney Popcorn, Indian Cowboy, Ocean of Pearls, and Pyaar Impossible!.

Working with Indian artists including Warren Mendonsa, Monali Thakur, Benny Dayal, Apeksha Dandekar and more, he produced some of the series most innovative and well received tracks.