Katakalon (Greek: Κατακαλών), rarely Katakalos (Κατακαλός), was the name of a Byzantine noble family of the 10th–12th centuries.
The first attested member of the family is Leo Katakalon, who served as Domestic of the Schools ca.
In the 11th century, due to their intermarriage with other aristocratic families, they often bore double surnames, while a branch of the family apparently assumed the name Maurokatakalon or Mavrokatakalon (Μαυροκατακαλών, "Black Katakalon").
The family became particularly prominent under the Komnenian emperors; Constantine Euphorbenos Katakalon was one of the most important generals of Alexios I Komnenos, and his son Nikephoros Katakalon wedded the Emperor's daughter Maria.
Likewise, Nicholas Maurokatakalon and his sons Marianos and Gregory were prominent military commanders at the time of Alexios I.