Her work has appeared in LGBT publications such as The Pink Paper, Gay News, Strip AIDS, Dyke's Delight, and AARGH, as well as The Guardian, The Independent, and New Internationalist.
[1] In 2015, her graphic novel Sally Heathcote: Suffragette (with Mary and Bryan Talbot) was included in a list published by The Guardian of the "top 10 books about revolutionaries".
[2] Sensible Footwear: A Girl’s Guide, her autobiography and history of gay and lesbian culture in England and Scotland from the end of World War II to the present, was published in 2018.
[4] Charlesworth's career in comics began in 1973, when she pitched a daily strip called "Twice Nightly" with two gay characters and suffragette themes to the Manchester Evening News.
[8] She has produced science comics for New Scientist ("Life, the Universe and (Almost) Everything") and The Independent, as well as illustrations for several books published by the National Museums of Scotland.
[21] She also produces various forms of 3-D art, including birthday cards, maps, board games, and shadow boxes, featured on her website.
She has opined that she feels the lesbian community of the time heavily self-policed behavior and look, which prevented her from fully realizing her identity and influenced much of her work.