McCarthy grew up in Brisbane where she initially pursued a career in cricket and represented Queensland in the process.
[2] She made her debut in the Lions' inaugural game against Melbourne at Casey Fields in the opening round of the 2017 AFL Women's season.
[10] McCarthy is noted for her speed and ability to kick the ball accurately while sprinting.
[15] In April 2019, McCarthy joined expansion club St Kilda, along with fellow Brisbane player Nat Exon.
Team Individual McCarthy joined Seven Network as a media personality supporting shows including Armchair Experts for the 2024 AFL season alongside Kane Cornes and the 2024 AFL Grand Final broadcast alongside Jude Bolton.