After her departure from a major label, Nash self-released her third studio album, Girl Talk, in 2013, but it failed to match the commercial success of her previous records.

In April 2007, Nash was signed to the Polydor offshoot Fiction Records[13] and the following month made her official TV performance debut on Later... with Jools Holland.

Following this success, the label announced plans to bring forward the release of Nash's debut album Made of Bricks to 6 August 2007.

Although her fifth single "Merry Happy" did not chart well in the UK, the song enjoyed minor success in other countries, including the United States and Canada.

In March 2009, Nash became one of the founding members of Featured Artists' Coalition, a nonprofit organization and lobbying group,[23] and revealed that she was in the early stages of recording her second album.

She was introduced by her boyfriend Ryan Jarman to Bernard Butler, the producer of Duffy's debut album Rockferry and a former guitarist for Suede.

[25] As a side project in late 2009, Kate joined a punk band called The Receders where she played bass guitar, with Jon Jackson and Brett Alaimo.

[27] In January 2010, Nash revealed that the album was complete, and the following month the song "I Just Love You More" was made available for free download from her official website.

To promote the record, the singer embarked on a tour, beginning with nine dates in North America in late April, with the all-female travelling festival Lilith Fair.

[39] Indie act Brigitte Aphrodite (who had toured with Kate on many occasions) was the first artist signed to the label and released the debut single "I Dream Myself Awake" in 2011.

[43] In February 2012, Nash wrote and recorded a song with some of the Occupy London protesters camping outside the St Paul's Cathedral, following workshops led by her and Sam Duckworth of Get Cape.

[49] The punk and grunge-influenced song, which Nash wrote, recorded and made a video for in under 24 hours,[50] received mostly negative feedback.

[51][52] As a fan of Buffy the Vampire Slayer, Kate staged a play based on the season six musical episode "Once More, with Feeling" at Hackney Picturehouse.

In 2014, Nash performed at the Coachella and Lollapalooza festivals, and released a new free single "She Rules" which was accompanied by a DIY music video filmed on a mobile phone.

[59][60] In the same year, she relocated to Los Angeles[61] and set up Girl Gang, an online support and networking hub for the feminist community.

Later that year, Nash discovered that her manager, Gary Marella, had been stealing large sums of money from her,[3] which resulted in near-bankruptcy.

In April 2017, she launched a Kickstarter campaign to finance a fourth studio album[64] and released an EP, Agenda, promoted by the single "Call Me".

Nash's fourth studio album, Yesterday Was Forever, was released independently on 30 March 2018, preceded by the singles "Drink About You" and "Life in Pink".

[72] Kate also appeared in a feature film Horrible Histories: The Movie – Rotten Romans and released two new singles in 2019: the grunge-inspired "Trash", in which she condemns environmental pollution, and the pop track "Bad Lieutenant".

Following the cancellation of GLOW before its fourth season could be completed due to the COVID-19 pandemic, Nash launched a Patreon page to connect with her fans more directly.

In October, the musical Only Gold had its world premiere at the MCC Theater in New York City, featuring score by Nash and book by Andy Blankenbuehler and Ted Malawer.

[81] In a sympathetic review, David Walsh, arts editor at the World Socialist Web Site deplores the fact that Nash is compelled to resort to OnlyFans to support her creative endeavors: “That performers have to resort to semi-pornography to earn a living brings to mind the general identification in the 18th century of actresses with prostitutes.”[82] Nash's biggest musical influences include Hole,[83] citing their 1994 record Live Through This as her favourite album.

[84] She is also influenced by riot grrrl group Bikini Kill, crediting lead vocalist Kathleen Hanna as her idol.

[87][88] Some of her earlier influences include Buzzcocks, Celine Dion, the Spice Girls, Nirvana, Mis-Teeq, the Beatles, Pink, Blink-182, and Sum 41.

[63][89] Beginning in the Girl Talk album era, Kate started to incorporate elements of punk rock and grunge into her work as well as 1990s-inspired visuals, notably in the music videos "She Rules" and "Trash".

The exhibition, which ran from November 2010 to April 2011, used Nash's music to demonstrate today's younger urban mode of Cockney English.

[93] In September 2009, Nash helped to raise funds for five-year-old Tilly Lockey, who lost her hands due to meningococcal disease.

Nash began dating Ryan Jarman in 2007, frontman of The Cribs, after meeting while they were both guests on an episode of the music television programme Later... with Jools Holland that year.

[98] The pair were reported to be planning to get married in early 2009,[98] but Jarman announced in March 2012 that they had broken up, in part due to his struggle with anorexia and other psychological problems.