Katharine Byron (née Edgar; October 25, 1903 – December 28, 1976), a Democrat, was a U.S. Congresswoman who represented the 6th congressional district of Maryland from May 27, 1941, to January 3, 1943.

Senator Louis E. McComas, who represented the 6th congressional district of Maryland.

[2] She was elected to Congress in a special election held May 27, 1941 to replace her husband, Representative William D. Byron, after his death in an airplane crash near Atlanta, Georgia on February 27, 1941.

[1] She advocated amending the Neutrality Act during World War II and gave one of five speeches on December 8, 1941, in favor of President Franklin Roosevelt's declaration of war on Japan.

[1] She did not seek re-election in 1942 and retired in Washington, D.C.[1] Byron died at Georgetown University Hospital on December 28, 1976.