The Institute was formed to harmonise Ecology and Technology by initiating collaborations between artists, scientists and explorers, as well as hands-on educational programmes and demonstration projects.
Gray co-founded the October Gallery in 1978, a charitable trust centred on showing the multicultural an avant-garde in Bloomsbury, London.
Gray was co-founder and artistic director of the Theater of All Possibilities from 1967 to 2009, which developed performances and strategies for long-duration interdisciplinary projects that, in some cases, spanned decades.
She produced Ornette: Made in America (1985), the documentary featuring musician and Free Jazz pioneer Ornette Coleman, directed by Shirley Clarke,[1] Coleman composed a piece called "Kathelin Gray" that was released on his 1986 album "Song X", co-led by Pat Metheny.
She has collaborated with William Burroughs, Brion Gysin, Steina and Woody Vasulka, Gustav Metzger and Godfrey Reggio.