[5] In 2019, Freese moved to the University of Texas at Austin, where she holds the Jeff and Gail Kodosky Endowed Chair in Physics.

[7] Her idea of indirect detection in the Earth is being pursued by the IceCube Neutrino Observatory experiment,[8] and the "wind" of dark matter particles felt as the Earth orbits the Milky Way (work with David Spergel) is being searched for in worldwide experiments.

[9] She has proposed a model known as "Cardassian expansion," in which dark energy is replaced with a modification of Einstein's equations.

[11] Freese has also worked on the beginnings of the universe, including the search for a successful inflationary theory to kick off the Big Bang.

In 2013, observations made by the European Space Agency's Planck Satellite show that the framework of natural inflation matches the data.

[20] Her brother, Andrew Freese, deceased, was Chief of Neurosurgery at Brandywine Hospital, and performed the first surgery for gene therapy on humans.

She covers the contributions of Fritz Zwicky, for example, who was recently profiled as "the most important astronomer you've never heard of" and "the father of dark matter" on Cosmos: A Spacetime Odyssey.