[2] After seven months in office, Rowe was formally inaugurated on February 8, 2019 as part of the university's annual Charter Day ceremony.

As the guest editor of the Shakespeare Quarterly's special issue on New Media, Rowe led the first open review of a traditional humanities journal on the web.

[9] Rowe was an English professor at Yale University from 1992 to 1998 before moving to Bryn Mawr College, where she stayed from 1998 to 2014.

She was the director for the Tri-College Digital Humanities Initiative, a coalition of faculty, students and staff from Bryn Mawr, Haverford and Swarthmore Colleges.

[10] She is also the co-founder and former chief executive officer of Luminary Digital Media, an organization that created reading apps for iPadOS in partnership with the Folger Shakespeare Library.

Mid-career, Rowe completed graduate work in Cinema and Media Studies at New York University's Tisch School of the Arts.