The Kathmandu Animal Treatment Centre Nepal was first conceived after Jan Salter visited the organization Help in Suffering in Jaipur, India.

The KAT Centre Nepal was registered as a non-profit charitable animal welfare organization in 2003, and officially opened its doors on 9 May 2004.

With KAT's current facilities, 100 to 120 female stray dogs are sterilized, vaccinated for rabies, de-wormed and treated for existing illness or injury each month.

Additionally, people call to ask the organization to help street dogs and cats in distress, and they frequently bring animals to the Centre who need emergency treatment or were abandoned.

Through school visits, distributing leaflets, inviting schools and other groups to visit the Centre, and conducting outreach activities, KAT encourages communities to care for local street dogs, sterilize their pets (many of whom live outdoors where they can easily breed), and call KAT when they see animals who need help.

[6] In addition to Animal Birth Control, Rescue & Treatment, and Humane Education, the KAT Centre conducts Pet Therapy in schools for disabled children and orphanages in Kathmandu.

The KAT Centre encourages volunteers from technical backgrounds such as veterinarians and vet nurses, as well as people with no animal care experience.