[4][5] She was raised by her mother on a pig farm in the south of the state, in a house where her great-great-great-grandmother, who was born a slave, formerly lived.

[2][5][10][11][12] On Election Day, Barnette filed a lawsuit against Montgomery County election officials claiming that the county violated state laws on pre-canvassing ballots prior to the opening of polls by notifying voters of potential problems with their mail-in ballots.

"[5] Barnette announced she would run to fill retiring Senator Pat Toomey's seat in early April 2021, and received endorsements from Michael Flynn and Sebastian Gorka.

[1][4][9][11] Barnette began to receive scrutiny over past tweets she had made, including some spreading the conspiracy theory that former President Barack Obama is a Muslim, and others that have been described as homophobic and Islamophobic.

[16] On May 15, 2022, images surfaced showing that Barnette had participated in the "Stop the Steal" rally that preceded the 2021 United States Capitol insurrection; though her campaign has denied participating in any acts of violence, she has stated that she "brought" three buses of "pissed off patriots" to the rally.

[17] Barnette finished third in the 2022 primary, behind Mehmet Oz and David McCormick, a loss she blamed on comments made by Fox News host Sean Hannity.

[24] According to The Tennessee Star, in 2022 Barnette ran "on a platform emphasizing free-market health care, border security, school choice, domestic energy production, tax reform, and protection of the unborn.