[7] On December 19, 2013, Disney–ABC Domestic Television and Katie Couric mutually agreed to cancel the show.

Colleagues Christiane Amanpour, Deborah Roberts, Sam Champion, Leo Jean, Matt Gutman, Richard Besser, Marci Gonzalez, Jim Avila, Dan Abrams, Josh Elliot, Brian Ross, and ABC World News Anchor Diane Sawyer made appearances on her show to report on events related to news.

Couric had The View co-host Whoopi Goldberg, Kelly Ripa and Michael Strahan of Live!

[5] In the process, ABC announced intentions to relinquish to its affiliates the final hour of its daytime programming lineup (3–4 p.m. Eastern Time), occupied at the time by the soap opera General Hospital, to make room for the new program.

[12] In March 2012, Couric and Zucker reportedly expressed concern to ABC executives about having the ABC Daytime talk show The Revolution as a possible lead-in to Katie due to the program's stagnant ratings and concerns of potential fan outcry should the launch of Katie result in the cancellation of General Hospital.

Although affiliates were encouraged to air Katie during the 3:00 p.m. timeslot (ET),[5][13][19] the actual airtime of the program varied from one market to another.

[26][27][28] James Poniewozik of Time questioned Couric's decision to move to daytime television, believing that she was better suited on the morning talk show Today.