A native of New Brunswick, New Jersey to Greek-American parents, Lionikis was one of three descendants of Greek immigrants to play in the All-American Girls Professional Baseball League, the others being Annastasia Batikis and Vickie Panos.

Lionikis went 0-for-4 at the plate in two games for the Grand Rapids Chicks and Peoria Redwings, playing at second base and pitching.

Lionikis was employed by Rutgers University as equipment manager for the Women's Athletic Department.

Previously, she was employed by Rutgers University Library's Special Collections Division as a secretary.

She was also a former New Brunswick Little League coach and played on champion tri-state basketball teams.