He has released six studio albums, a wordless graphic novel titled Gloaming, published by Pocko,[3][4] and a book of poetry called Idiot Verse.

[7] In November 2010, his debut album Dear... was released on Motive Sounds Recordings, in a self-made limited edition.

In November 2012, Henson designed a t-shirt for the Yellow Bird Project to raise money for the Teenage Cancer Trust.

The album was released as a limited book edition, featuring illustrations made by different artists accompanying the songs.

His art show "Hithermost" took place at the Pertwee, Anderson & Gold gallery in London in January 2013 and "sold quickly".

On 16 June 2014, he performed at the Queen Elizabeth Hall in London as part of the James Lavelle-curated Meltdown festival.

[20] On the day of the concert, Henson released the album Romantic Works, featuring cellist Ren Ford.

In early 2015, Henson composed a score for Young Men, a dance project from BalletBoyz, which was performed at the Sadler's Wells Theatre in London as a co-production with 14–18 NOW.

The 70-minute work was jointly commissioned by the Barbican, Vivid Sydney, and National Concert Hall, Dublin.

Recorded at the same time as Monument, it features eight tracks, including "Marionette", a collaboration with Julien Baker, and the singles "Before Growing Old", "Limb", and "No Love Lost."

[26] On 17 October 2022, Keaton released a video on his newly-made TikTok account asking fans to request songs for him to perform covers of.

[citation needed] "The Meeting Place" was released on 15 March 2023 accompanied by an animation video; described in reviews and interviews as something on the soundtrack of "10 Things I Hate About You".

Henson has appeared on The Flight's EP Hangman, The Staves EP Mexico and with the London electronic group Unkle on several tracks including "Farewell", "Sonata" and "Sick Lullaby" from The Road: Part 1 and "The First Time I Ever Saw Your Face" from The Road: Part II (Lost Highway).

[28] Henson's music has featured in the BBC Three zombie drama In the Flesh (2013–2014), Derek, Elementary, The Blacklist and in the 2014 film X+Y (known as A Brilliant Young Mind in the U.S.).