Keenes is a village in Wayne County, Illinois, United States.

According to the 2010 census, Keenes has a total area of 0.13 square miles (0.34 km2), all land.

There were 46 housing units at an average density of 354.2 per square mile (136.8/km2).

17.9% of all households were made up of individuals, and 10.3% had someone living alone who was 65 years of age or older.

There were 35.3% of families and 40.4% of the population living below the poverty line, including 62.1% of under eighteens and 58.3% of those over 64.