Nagpure is best known for her portrayal of Siddhi Malik Chopra in Parichay, Nandini Pandey Raghuvanshi in Desh Ki Beti Nandini and Tulsi Trivedi in Pyar Ka Pehla Naam: Radha Mohan.
[1][2] Nagpure started her career with Star Pravah Talent Hunt Competition.
She made her acting debut with the Marathi serial Olakh portraying Vibhavari "Vibha" Talwarkar from 2010 to 2011.
Nagpure made her Hindi television debut with Parichay portraying Siddhi Malik Chopra opposite Samir Soni from 2011 to 2013.
[11] The same year, she made her web debut with Sony LIV's Shaurya portraying Vineeta Ashok Kamte opposite Raqesh Bapat.