Keeseville is a hamlet (and census-designated place) in Clinton and Essex counties, New York, United States.

The hamlet was originally called "Anderson Falls" by settlers from New England, who moved into the area following the American Revolutionary War and forcing of Iroquois tribes off their lands.

The early hamlet was an industrial area devoted, in part, to lumber, iron processing and milling.

The "Peanut RR" was a 5.6 mile shortline, of traditional American Standard Gauge width to allow easy transfer onto the rest of the U.S. rail network.

The former train station, long North Country Club Restaurant, received a historic roadside marker on May 19, 2018.

Visit Anderson Falls Heritage Society, 96 Clinton Street in Keeseville, to experience local history.

[7] Keeseville is located at 44°30′13″N 73°28′52″W / 44.50361°N 73.48111°W / 44.50361; -73.48111 (44.503688, -73.481087),[8] south of Plattsburgh, just west of Lake Champlain, within the Adirondack Park.

The Ausable River, forming the boundary between Clinton and Essex counties, flows through the village.

[12][13] Keeseville is the birthplace of William Henry Jackson, born April 4, 1843, who became a renowned photographer of the frontier and the Civil War.

His photographs of the American frontier are famous, and his glass negatives are held in museums around the United States.

He was active in upstate New York, designing churches and public buildings in the late 19th century that have been listed on the National Register of Historic Places.