[2] Its southern terminus is at County Route 66 between Amboy and Chambless.

The road then continues as California State Route 127 northward to Nevada, connecting to Nevada State Route 373, passing near Death Valley National Park.

From there, Kelbaker Road continues northeast between the Granite Mountains on the west and Providence Mountains to the east, over the 4,035-foot (1,230 m) Granite Pass, and then north past the eastern edge of the Kelso Dunes to the community of Kelso.

The road then continues north after crossing the wash, then turns west approximately 11 miles (18 km) to Baker.

Kelbaker Road is the primary route through Kelso and the Mojave National Preserve, and thus passes by or connects to points of interest such as:[1][2]