He was selected by the Baltimore Ravens in the second round of the 2012 NFL draft, and was a rookie starter throughout the team's Super Bowl XLVII championship run that season.

[2] Osemele was born and raised in Houston, where he attended Langham Creek High School.

[4] Entering his senior season at Iowa State in 2011, Osemele had started 30 consecutive games.

[10] Osemele successfully recovered from back surgery and started all but two games for the Ravens in the 2014 season.

[12] He was selected to his first Pro Bowl for the 2016 season along with fellow Raider offensive linemen Donald Penn and Rodney Hudson.

[15] On December 19, 2017, Osemele was named to his second Pro Bowl along with fellow Raider offensive linemen Donald Penn and Rodney Hudson for the second straight year.