Her work's focus is on understanding the clinical and psychosocial implications of genetic testing for BRCA gene mutations in women, men and their families.
[2] Upon earning her PhD, Metcalfe returned to WCH and accepted a faculty position at U of T. In 2004, she led a research team in surveying half of 120 women in Ontario who had preventive double mastectomies between 1991 and 2000.
[5] As such, she received another grant in 2012 while working as U of T's Bloomberg Nursing interim director of research to develop and test a decision support tool for post-mastectomy breast reconstruction.
[13] In 2018, Metcalfe was appointed Acting Associate Dean, Research & External Affairs for a one year term while Linda McGillis Hall was on administrative leave.
[14] Following her one year term, Metcalfe became the co-Principal investigator on a project entitled "Outcomes Associated with Direct Rapid Genetic Testing at Time of Breast Cancer Diagnosis.