The Kema (Russian: Ке́ма) is a river in the Vytegorsky and Vashkinsky districts of Vologda Oblast in Russia.

The source of the Kema is Lake Kemskoye in the north of Vytegorsky District.

The river flows in the general direction south and enters Vashkinsky District.

It accepts the Indomanka River from the left and turns southwest.

The Kema River freezes up in early November and stays icebound until late April.