[4] After a couple of high finishes, Venturi reached the pinnacle of his comeback by winning the U.S. Open in 1964 at Congressional Country Club, after nearly collapsing in the near-100 °F (38 °C) heat and humidity of the 36-hole final day.

[17][18] He played on the Ryder Cup team in 1965,[9][11] and received the 1998 Old Tom Morris Award from the Golf Course Superintendents Association of America, GCSAA's highest honor.

[21] Defending his title at the U.S. Open in June, Venturi continued to have difficulty with his hands and entered the championship with plans to have surgery the following week.

[11] Venturi's condition improved and he won a tour event in January 1966 at the very familiar Harding Park in his hometown,[25][26] but he soon relapsed; after additional surgeries, he could not regain his form.

[27] After retiring from the Tour in 1967 with a total of 14 career wins, Venturi spent the next 35 years working as a color commentator and lead analyst for CBS Sports – the longest lead analyst stint in sports broadcasting history,[9] made remarkable by the fact that he had a stutter, which was less manageable early in life.

[29] Venturi appeared in the 1996 film Tin Cup, portraying himself as a commentator at the U.S. Open, held at a fictional course in North Carolina.

In one scene, Venturi is shown voicing his opinion that the film's protagonist, Roy McAvoy (Kevin Costner), should lay up on a long par-5 rather than try to reach the green in two shots.

Venturi is survived by his third wife Kathleen, two sons, Matthew and Tim and four adult grandchildren Peter, Andrew, Sara and Gianna.