From 1996 to 1997, Yoshino served as a law clerk for Judge Guido Calabresi of the U.S. Court of Appeals for the Second Circuit.
[citation needed] His major areas of interest include social dynamics, conformity and assimilation, as well as queer (LGBT) and personal liberty issues.
[citation needed] During the 2006-2007 and 2007-2008 school years, he served as a visiting professor at New York University School of Law, and in February 2008 he accepted a full-time tenured position as the Chief Justice Earl Warren Professor of Constitutional Law.
[7] In July 2023, following a recommendation from the oversight board to deplatform Cambodian head of state Hun Sen, the government of Cambodia listed Yoshino as one of 22 people connected with Meta who were banned from entering the country.
[8] A Japanese American, and openly gay man, Yoshino writes poetry for personal enjoyment.