[2] Offit is also a member of the Program in Cancer Biology and Genetics at the Sloan-Kettering Institute and Professor of Medicine and Healthcare Policy and Research at Weill Cornell Medical College.

[3] He was previously a member of both the Board of Scientific Counselors of the National Cancer Institute[4] and the Evaluation of Genomic Applications in Practice and Prevention working group of the U.S. Centers for Disease Control.

[10] In 2023, he was awarded University of Pennsylvania's Basser Global Prize for BRCA1 and BRCA2-related research[11] and an Ellis Island Medal of Honor for his national professional and civic contributions.

[16] Offit and other trustees would further propose that residential colleges be expanded to include upperclassmen who had not joined a selective eating club—a reform that, with some modification, would be adopted decades later.

[11] In 1997, he wrote Clinical Cancer Genetics: Risk Counseling and Management, which received an award in Medical Sciences from the Association of American Publishers.

[23] In 2002, Offit and his clinical team published the first prospective study establishing the role of risk-reducing ovarian surgery in women carrying BRCA1 and BRCA2 mutations.

[26] In 2018, Offit joined Beth Karlan, Judy Garber, Susan Domchek, and other physicians to launch the BRCA Founder Outreach Study (BFOR).