According to the Caves, Lakes, and Corvettes regional brochure by the Kentucky Department of Tourism, the entire KY 100 corridor is considered a Kentucky Scenic Byway.

Its original western terminus was located near downtown Russellville, and its eastern terminus was originally located about 3 miles (4.8 km) west of Burkesville on KY 90.

The remaining parts of the original alignment in western Cumberland County are either no longer existing (especially the originally unpaved section) or they still exist, but is now maintained by the Cumberland County Road Department.

[5] In 2015, KY 100's western terminus was truncated to a crossroads intersection with U.S. Route 68 and US 68 Business on the east side of Russellville.

[6] In 2018, the western terminus was truncated again to Franklin Road's intersection with the then-new southern loop of the Russellville Bypass with the US 79 designation.