Kentucky Route 5 (KY 5) is an 11.573-mile-long (18.625 km) north–south state highway in eastern Kentucky.

KY 5 begins at a junction with U.S. Route 60 at Princess, Kentucky in Boyd County.

The route continues through Bellefonte in Greenup County to terminate at U.S. Route 23 back in Boyd County in between Ashland and Russell.