Kentucky Route 750 (KY 750) is a 3.7-mile-long (6.0 km) east–west state highway located within Greenup County.

KY 750 is routed over Pond Run Road and Raceland Avenue in Raceland, Lexington Avenue and Powell Lane in Flatwoods and Seaton Avenue and Kenwood Drive in Russell.

KY 750 is mostly a two-lane route that connects Raceland and Russell via Flatwoods.

It was widened to three lanes for a little under one mile (1.6 km) in Raceland in 2005.

Before reconstruction, it was notorious for its narrow width, where buses and automobiles frequently had to drive on the sidewalk to prevent from colliding with another vehicle.