Ketevan Pkheidze was born into a princely family in Imereti, a kingdom in western Georgia, tracing their origin to the 11th century.
The branch to which Ketevan belonged had their estate centered at the village of Zedubani.
[1] Ketevan married Heraclius II in 1740, shortly after the prince repudiated his engagement (or actual marriage according to traditional accounts of Prince Vakhushti, Marie-Félicité Brosset, and Cyril Toumanoff[2]) with Princess Ketevan Orbeliani, who thereafter retired to a monastery.
Whoever was his consort, Heraclius had two children of his first marriage, Princess Rusudan (died in infancy) and Prince Vakhtang.
Ketevan died of a severe illness in Telavi, being mourned by Heraclius and his father Teimuraz II, King of Kartli, who had arrived in Kakheti only to find his daughter-in-law dead.