After starting out at Benfica and Porto, representing only the youth teams in the first case and the youths and the reserves in the second,[1][2] he began his professional career in Sweden with Landskrona BoIS (where he played alongside brother Kingsley) and, after two years, returned to Portugal, appearing for Vitória de Setúbal in the Primeira Liga.

[4] However, he returned to Sweden in December of the same year to play for IFK Norrköping in the top level – the transfer fee was this time reported as €300,000.

After a brief stint in Romania with Politehnica Timişoara, Amuneke moved back to Portugal, signing with Madeira's Nacional in early July 2009.

On 21 December 2016, after a stint at Ballynure Old Boys of the Ballymena & Provincial Football League, he moved to the NIFL Premiership having agreed to a short-term deal at Linfield.

Amuneke won two caps for Nigeria, both during the 2006 FIFA World Cup qualifiers, featuring against Rwanda and Angola in June 2005.