Khamgaon is known for being one of the hottest cities in Maharashtra with temperature often hitting 47–48 degrees Celsius during summer.

Also, the rainfall is pretty low in the region which has led to water scarcity many times in the city over the past.

Mahatma Gandhi stayed here for a brief time during indian freedom movement, they inaugurated Tilak Rashriya Vidyapeeth in the city.

The place is said to owe its start in commercial life to the good management of one Jetal Khan, a revenue collector, who invited and encouraged traders.

The great camps of Pendharis were followed by many merchants and brokers who made big gains by buying up the booty.

In 1818 Colonel Doveton broke up a large horde of Pendharis at a village close to Khamgaon.

They were forced to disband and scatter, so the honest prize agents of this camp settled at Khamgaon and their descendants became virtuous dealers of cotton in particular and other merchandise in general.

Along with this, Diwali, Holi, Cheti Chand, Eid Baba Mastan Urs, And Syed Thikri Shah Miya Urs, Near Syed Baada (Traditional House of Syed) Mastan chowk, Dashera, Dr. Babasaheb Ambedkar Jayanti, Chhatrapati Shivaji Maharaj Jayanti, Mahavir jayanti, Kawad Yatra, and Ram Navmi are the major festivals of the City.

Ganesh Utsav of Khamgaon is unique, near about 30 mandals in sequence take part in a procession along traditional path.

Beginning on Kojagiri Purnima, the festival honors the deity Jagdamba with rituals and prayers to calm her "fierce" red visage, symbolizing victory and her return after defeating demons.

Silver sterling tubes made in Khamgaon by the Chandrayaan mission have taken a leap into space.

The conductive silver tube is manufactured at Shraddha Refinery in Khamgaon Industrial Estate (KIE).

The contract to manufacture silver sterling tubes was awarded by ISRO on June 3, 2020 in Khamgaon.

The city is served by the Khamgaon railway station, which was built during the British Raj.

[5] Khamgoan Terminus railways station which runs a local train between Khamgaon to Jalamb there is a special direct train from Khamgaon to Pandharpur during Aashadhi Ekadashi wari the nearest railway stations are Malkapur, Jalamb Junction, Shegaon and Akola Junction, from which connections can be made to the broader rail network.